selected publications
- Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
- Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer. Cancer cell. 2024 Academic Article GET IT
- A Second Space Age Spanning Omics, Platforms, and Medicine Across Orbits. Nature. 2024 Review GET IT
- Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight. Nature microbiology. 2024 Academic Article GET IT
- Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew. Nature. 2024 Academic Article GET IT
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Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Nature communications.
2024
Academic Article
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Times cited: 24 - Space radiation damage rescued by inhibition of key spaceflight associated miRNAs. Nature communications. 2024 Academic Article GET IT
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Spaceflight induces changes in gene expression profiles linked to insulin and estrogen.
Communications biology.
2024
Academic Article
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Times cited: 11 -
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight.
Nature communications.
2024
Academic Article
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Times cited: 13 - The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature. 2024 Academic Article GET IT
- Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology. Communications medicine. 2024 Academic Article GET IT
- A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection. European journal of human genetics : EJHG. 2023 Review GET IT
- Elevated A-to-I RNA editing in COVID-19 infected individuals. NAR genomics and bioinformatics. 2023 Academic Article GET IT
- Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation. 2023 GET IT
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Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells.
Stem cell reports.
2023
Academic Article
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Times cited: 3 - Spatial omics technologies at multimodal and single cell/subcellular level. Genome biology. 2022 Review GET IT
- Challenges and considerations for single-cell and spatially resolved transcriptomics sample collection during spaceflight. Cell reports methods. 2022 Review GET IT
- IL6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease. Journal of hepatology. 2022 Academic Article GET IT
- CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nature cell biology. 2022 Academic Article GET IT
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System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
Cell reports. Medicine.
2022
Academic Article
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Times cited: 31 - Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease. Cell reports. 2021 Academic Article GET IT
- Cell and Tissue Therapy for the Treatment of Chronic Liver Disease. Annual review of biomedical engineering. 2021 Information Resource GET IT
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The spatial landscape of lung pathology during COVID-19 progression.
Nature.
2021
Academic Article
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Times cited: 249 -
Peptide-based scaffolds for the culture and maintenance of primary human hepatocytes.
Scientific reports.
2021
Academic Article
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Times cited: 27 -
Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells.
Gastroenterology.
2020
Academic Article
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Times cited: 33 -
An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo.
Science translational medicine.
2018
Academic Article
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Times cited: 83