administers grant (PQ1) Adaptive immune and microbial mechanisms regulating Lynch syndrome penetrance A randomized, placebo-controlled clinical trial examining the efficacy of Fecal Microbiota Transplantation (FMT) and subsequent dietary fiber in patients with moderate ulcerative colitis (MINDFUL) Biopharma Agreement CAP-IT Center for LNP RNA Immunoprevention CHASE-EIM: Cohort for Healing Arthritis, Skin, and Eye Extra-Intestinal Manifestations CTLA-4 regulation of intestinal health and inflammation Cancer Immune-Interception for Lynch Syndrome Colorectal Cancer Prevention by a novel EPA analogue TP-252 and naproxen in FAP and lynch syndrome models Core B: Human Hepatocyte and Discovery Defining a novel mechanism of mucosal healing Defining a novel regulator of innate lymphoid cells and intestinal health Defining host-microbe interactions in cancer and immunotherapy Defining mechanisms of immune tolerance to the intestinal microbiota Defining novel mechanisms of microbiota in regulating anti-tumor responses Delineating the role of genetic mutations in Hepatoblastoma development and phenotypes EA Pharma Research Collaboration Agreement Elucidating the Role of MALAT1 Somatic Driver Mutations in Colorectal Cancer Emerging Therapeutic Paradigms in Inflammatory Bowel Disease Enhancing Immune Regulation In Gene Therapy For Hemophilia Fiber-induced Metabolites Promote UC Healing GARDE: Scalable Clinical Decision Support for Individualized Cancer Risk Management Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial Immune regulation of intestinal health and disease In search of an HBV cure: novel model systems and targets Innate immune regulation of host-microbe interactions Innate immune regulation of neuroinflammation Innate lymphoid cell regulation of the host-microbiota interactions in cancer Innate-like lymphocyte regulation of host-microbiota interactions in cancer Integrated high-throughput functional assays to identify ulcerative colitis causal risk variants Interleukin-2 regulation of mucosal inflammation Interrogation of a Novel Immuno-Regulatory Pathway in Colitis-Associated Cancer Investigating molecular mechanisms behind gut bacterial transamination and IBD Launching HBV with RNA to assess antiviral resistance and explore fundamental aspects of virus-host biology Leveraging the Gut Microbiome to Regulate Hepatic Gluconeogenesis Long Title: System-Level Capture of Family History Data to Assess Risk of Cancer and provide Longitudinal Care Coordination Mechanisms of epithelial-mesenchymal crosstalk in intrahepatic biliary formation Medication Utilization and Pricing for Patients With Viral Hepatitis Microbiota, Metabolites, and Colon Neoplasia Mid-terminal human synthetic liver organogenesis Modeling alcohol toxicity in human hepatocytes Molecular and clinical characterization of IBD patients naive or refractory to standard of care over time Multidisciplinary Research Training in Gastroenterology and Hepatology Multidisciplinary Research Training in Gastroenterology and Hepatology Neoantigen Vaccination for Lynch Syndrome Immunoprevention Novel mechanisms protecting the gut from TNF Optimization of the engineered 3D hepatic microenvironment enhances pluripotent stem cell derived hepatocyte PREVENT Cancer Preclinical Drug Development Program: Preclinical Efficacy and Intermediate Endpoint Biomarkers Piloting a Standarized Care Pathway to Improve Risk Stratification and Management of Patients with Nonalcoholic Fatty Liver Disease (NAFLD) Pregnancy in Inflammatory Bowel Disease And Neonatal Outcomes (PIANO) Project 3: Mechanisms of Innate and Adaptive Immune Responses to AAV-FVIII Gene Transfer Regulation of Enteric Nervous System Function by Group 3 Innate Lymphoid Cells Regulation of gut damage and inflammation through insulin-like growth factor-1 Role for TL1A in innate intestinal inflammation and colitis associated cancer TL1A Regulation of Group 3 Innate Lymphoid Cells in Colitis Them1 Inhibitors for the Management of Non-Alcoholic Fatty Liver Disease Thioesterase-mediated lipotoxicity in liver and thermogenic adipose tissue Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiency Vaccines against Fusobacterium Nucleatum for FAP- and Lynch Syndrome-associated-Option Validating novel DNA repair deficient cancer therapy targets and small molecule compounds